Dr.vijay shinde, S20727
Hyperhomocysteinemia is a known to be risk factor for CRVO. We report a case of CRVO associated with hyperhomocysteinemia with decreased vit.B12 ,in absence of any other systemic illness .45 yr.male patient ,c/o DOV LE since 1 month, sudden painless.past,personal,addiction,family,systemic illness hisory -not significant.On examination-BCVA RE-6/9,LE -5/60.Anterior segment -normal BE. Fundus examination-LE- dilated tortuos veins,superficial hmgs. illdefined dics margins.s/o CRVO. Confirmed on FFA .OCT was done to know CFT -451. Routine inv.cbc,rft,lft,lipid,BP,RBS,Coagulation profile,CVS,FA all were normal.pt.was given inj.anti-vegf .But recurrence of same compaints even after 2 inj.Then we did plasma homocysteine were altered.with homocysteine-68 units. pt.was given vit b12 suppliment with inj anti vegf. After 2 month LE -6/18 with near nomal fundus. Pt.is having no c/o till date.So the responce of anti- vegf supplemented by taking c/o risk factors e.g sr.homocysteine and vit b12.


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