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FP823 : A case of High grade Neuroendocrine carcinoma presenting with Proptosis

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FP823 : A case of High grade Neuroendocrine carcinoma presenting with Proptosis

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Dr.SALONI PATEL, S21457

BACKGROUND:

NEC are rare,highly aggressive neoplasms that infrequently metastasize to the orbit.

METHOD:

A 78 years old male presented with swelling & decreased vision of right eye since 15 days. Physical examination confirmed a R/E proptosis with extraocular movements restricted in all gazes.MRI Brain & Orbit revealed an intraosseous neoplastic lesion involving lateral wall of right orbit & adjacent temporal bone. Orbital mass biopsy indicated possibility of poorly differentiated malignant epithelial tumor. IHC was suggestive of high grade neuroendocrine carcinoma.

RESULT:

Further workup was done to find the primary site & PETscan revealed a soft tissue lesion involving upper lobe of left lung. Patient was referred to oncologist & is currently receiving chemotherapy. Visual acuity is improving after it.

CONCLUSION:

NEC with orbit metastasis is very rare but associated with indolent course & prolonged survival,hence early treatment of orbit metastasis can help prevent visual loss.

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