Dr.prerna agrawal, A17847
Background: A distinct and continuous IS/OS(Inner segment/Outer segment) junction indicates normal alignment of membranous discs. Disruption of IS/OS junction on Optical Coherence Tomography, may reveal damage to macular photoreceptors.
Aim: To study the correlation between visual acuity and foveal microstructural changes in diabetic macular edema.
Methods: It is a cross sectional observational study of 100 patients in Diabetic Macular Edema. The IS/OSline was evaluated and graded according to their length of disruption.The central subfield thickness(CST) was evaluated as the average retinal thickness of the 1 millimeter central scanned area.
Results: The IS/OS Scores were highly correlated with the Best Corrected Visual Acuity (BCVA) and this correlation coefficient was higher than the correlation between CST and BCVA.
Conclusions: Well preserved IS/OS Junction is a much more strong predictor of visual potential than Central Subfield Thickness.
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