Dr.Pallak Kusumgar, P16857
Aim: To quantify change in corneal stiffness (kc) relative to topographical changes after accelerated CXL.
Methods: 111 keratoconic (KC) eyes were analyzed 3 months after CXL using Corvis-ST and Pentacam HR. Corvis deformation waveform was analyzed using a novel analytical biomechanical model to derive kc. The cohort was then grouped based on kc into decreased (<-5%), no change (+/-5%) and increased (>+5%).
Results: Pentacam (except aberrations) and Corvis indices showed no changes at 3 months. Change after surgery in kc were -17%, <0.5% and +19% (p<0.01); for above groups respectively. The trend seen in kc was also observed in higher and lower order RMS of aberrations. Conclusion: Corneal stiffness can be accurately quantified using this technique, probably indicating true biomechanical stiffening in vivo, which cannot be detected by present day conventional methods. This can have far reached implications in both KC eyes and refractive surgery with additional crosslinking procedure.
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