FP254 : Comparision of Topical olopatadine hydrochloride with ketotifen fumarate for allergic conjunctivitis

Dr.Pallavi Ghule, P21100

Allergic conjunctivitis (AC) is associated with itching, redness, tearing, pain, and burning sensation in the eyes. The purpose of this study was to compare topical olopatadine & ketotifen in terms of effectiveness and safety for the management of AC. Methods: Patients clinically diagnosed with AC were randomized into 2 groups of 30 patients each & received either topical olopatadine HCl 0.1% or ketotifen fumarate 0.025%. They were followed up on the 4th, 15th, & 30th days to evaluate symptoms, signs, & quality of life (QOL) scoring. Results: There were a total of 60 patients (34 men and 26 women) Compared with ketotifen, olopatadine significantly reduced itching, tearing, hyperemia, & total AC scores by the 4th day & conjunctival papillae by the 15th day. Adverse reactions were reported in 10% & 18% of patients treated with olopatadine & ketotifen, respectively. Conclusion: Compared to ketotifen, olopatadine provided quicker relief of symptoms, & improved QOL, with fewer side effects.