Dr.Anand Singh Brar, B20980
Purpose: To compare visual and anatomical outcomes of femtosecond laser assisted in situ keratomileusis(FS-LASIK) and small incision lenticule extraction(SMILE) in moderate-high myopia
Methods: Prospective comparative evaluation of 80 eyes undergoing FS-LASIK (n=40) or SMILE (n=40). Primary outcome measures were visual acuity and quality. Secondary outcome measures were ocular surface stability, corneal biomechanics and subbasal nerve fibre density (SNFD). Follow up was performed on day 1, 30 and 6 months.
Results: At 6 months, UCVA was comparable in both groups (p=0.65). Visual quality (higher order aberrations) was significantly better with SMILE (p<0.001). Tear-film breakup time (p<0.001), Schirmer test (p=0.02) and SNFD (p<0.001) was significantly better in SMILE group at all follow-up visits. Ocular hysteresis was better in SMILE group (p<0.001).
Conclusion: SMILE leads to better visual quality, ocular surface and biomechanical stability as compared with FS-LASIK.


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