Dr.Jaya Kaushik, K12383
Purpose – To study the effects of assisted reproductive technology (ART) on various ocular assessment. Method- 117 women undergoing ART were enrolled, the outcome measures were IOP, CCT, Endothelial Count, Schirmers test 1 done at baseline, post oral contraceptive, post GnRH agonist, post conception, third trimaster of pregnancy. Results: Out of 117 women enrolled for in vitro fertilisation, only 48 patients conceived. 16 women had abortions and remaining 32 women, who had childbirth were followed until three months post-partum. Baseline mean IOP showed a slight decrement and corneal pachymetry and corneal endothelial cell counts showed slight increment from phases V1 to V4 of ART but statistically they were not significant (p>0.05). Conclusion- The ocular physiological changes in various phases of ART were nonspecific, The ART appears to affect tear secretion as measured by Schirmers test 1.
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