Dr.Dibya Prabha, D21447
Abstract: Opticospinal MS is a MS subtype with propensity to involve predominantly optic nerve & spinal cord. Some cases are positive for AQP4 antibody suggesting NMO spectral disorder( autoimmune disease characterised by recurrent attack of optic neuritis & myelitis)
Objective: ophthalmologic & neurologic signs & symptoms were assessed in a patient diagnosed bilateral ON associated with opticospinal MS.Here reporting a case of 40year old woman presented with sudden onset bilateral loss of vision, paralysis of both lower limb, tingling sensation below umbilicus.The complete ophthalmologic exam(clinical exam, fundus photography,OCT) along with MRI,CT,CSF exam.aquaporin antibody supported diagnosis of MS with ON & longitudinally extensive transverse myelitis (LETM)
Results:LETM is not seen with MS so, always consider for NMOSD or opticospinal MS in Asian. Multidisciplinary approach of case played important role in early establishment of diagnosis & functional recovery of this patient.


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