FP855 : Varied ocular manifestations of Marfan’s Syndrome in a family

Dr.Jyoti Deswal, D17716

We present the case of 4 members of a family presenting with Marfan syndrome showing myriad of ocular manifestations. The father 45 yrs, presented with bilateral ectopia lentis with highIOP. His eldest daughter 18 yrs, also shared similar findings. His second daughter 14yrs had inferiorly subluxated lens in one eye and anteriorly dislocated lens with corneal opacity in other. Third daughter 13 yrs had intercalary and equatorial staphyloma with anteriorly dislocated lens with flat AC and raised IOP in right eye and inferiorly subluxated lens in left eye. There was history of death of a male child in the family due to some systemic disease at the age of 8. Cardiovascular and neurological examination was normal. Hands and fingers were long and slender with hyperflexible joints. The ophthalmological management of Marfan patients is challenging and periodic followup is needed. Each case needs to be evaluated individually to analyse the risks and benefits of the procedures.