Dr.Suneel Sangaraju, S21409
Purpose:
To study the ocular biometric parameters in PACD patients and to compare them with normal control subjects,
To identify role of genetic polymorphisms in PCMTD1 and COL11A1 genes in our population in PACD pathogenesis.
Materials and methods:
Total 200 eyes of 100 PACD patients and 200 eyes of 100 control subjects were included in the study. PACD patients were further divided into subgroups PACS, PAC and PACG based on ISGEO classification system and perform various biometric measurements and genotping.
Results:
PACD patients were having significantly shorter AXL, shallow ACDs , thicker lenses and steeper corneas when compared to normal control subjects.
Genotyping of PCMTD1, NM_001286783.1:c.215C>T and COL11A1, NM_080629.2:c.2386C>G polymorphism yielded no significant association with PACD( p values were 0.6 and 0.8 respectively).
Conclusion:
Ocular biometric parameters do vary significantly in PACD patients when compared to normal subjects.
PRESENTATION NOT RECEIVED FROM THE AUTHOR.
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